4-Quinoline Formaldehyde'in uygulama ve araştırma

4-Quinolinecarboxaldehyde, also known as 4-formylquinoline or quinoline-4-carboxaldehyde, is an organic compound that appears as a pale yellow solid. As a type of quinoline and its derivatives, it is an important pharmaceutical intermediate that can be synthesized from aniline hydrochloride and ethylene ketone through Doebmer Miller reaction and Riley oxidation reaction [1-2].

uygulama

Quinoline-4-carboxaldehyde thiosemicarbazone (QLATs) was synthesized by refluxing amino sulfur gland and 4-quinolone formaldehyde as raw materials, anhydrous ethanol as solvent, and acetic acid as catalyst. Its melting point, UV and IR spectra were measured, and its effect on H+was investigated by UV visible absorption spectroscopy. The absorption peak of QLATS solution is located at 352nm. With the increase of acidity, the absorption band of QLATS undergoes a red shift, and the shape and intensity of the absorption spectrum gradually change. At pH 7.22, QLATS is colorless and yellow under acidic conditions. It is easy to operate and has good sensitivity.

Regarding research

Polyoxometalates are metal oxygen clusters formed by connecting pre transition metals with oxygen ligands. Polyoxometalates have a wide variety of types and complex structures. Due to their rich physical properties such as light, electricity, magnetism, catalysis, and biological activity, they have potential applications in catalysis, materials, medicine, and other fields. Organic covalent modification of polyacids is the use of organic ligands to replace the terminal oxygen, bridging oxygen, or coordinating atoms of polyacid clusters to form derivatives. Due to its ability to improve the properties of polyacids, it is currently a hot topic in the field of polyacid research, and pre - and post modification strategies have been developed to modify polyacids.

To further investigate the preparation, structure, and properties of Anderson polyoxometalate organic derivatives, researchers employed a post modification strategy to prepare polyoxometalate based molecular rods [Bu4N] 3 [MnMo6O (18) {(OCH2) 3NH2} 2] and [Bu4N] 3 [MnMo6O (18) ((OCH2) 3CN=CH-4-Py) 2] (POM-1) and [Bu4N] 3 [MnMo6O (18) (((OCH2) 3C-N=CH-3-Py) 2] (POM-2) containing pyridine groups through imidization reactions with 4-carboxaldehyde pyridine and 3-carboxaldehyde pyridine, respectively. Using POM-1 and POM-2 as connecting ligands to coordinate and assemble with the metal building units of [Cu (PPh3) 2 (CH3CN) 2] ClO4 (CuP2), one-dimensional chain like coordination polymers were obtained by assembling POM-1 and CuP2; POM-2 and CuP2 were assembled to form two two-dimensional network coordination polymers, achieving controllable coordination assembly.