tert-Butyl 4-[4-(4,4,5,5-tetrametil-1,3,2-dioksaborolan-2-yl)-1H-pirazol-1-il]piperidin-1-karboksilat

4- [4- (4,4,5,5-tetramethyl-1,3,2-dioxacycloboran-2-yl) -1H-pyrazol-1-yl] piperidine-1-carboxylic acid tert butyl ester is an organic compound commonly referred to as TBDPS. The following is an introduction to the properties, uses, preparation methods, and safety information of the compound:

doğa:

-Appearance: White solid

-Thermal stability: Stable

Görev:

-TBDPS is a commonly used protective group that can be used to protect functional groups such as alcohols, phenols, and amines from accidental reactions or damage during chemical reactions.

Üretim yöntemi:

The synthesis of TBDPS is mainly carried out through the following steps:

-Reacting pyridine with 1H-pyrazole-1-carboxylic acid to generate 1-piperidine-1H-pyrazole-1-carboxylic acid ester.

-Then, the ester group was cleaved using sodium hydroxide induced by boric acid to obtain the target product TBDPS.

Güvenlik Bilgileri:

TBDPS is relatively safe under normal conditions, but it still needs to be used and stored with caution, taking note of the following:

-TBDPS may be irritating to the eyes and skin, and should be immediately rinsed with water upon contact.

-When operating TBDPS, appropriate personal protective equipment such as gloves, goggles, etc. should be worn.

-TBDPS should be stored in a dry, cool place, away from sources of fire and flammable materials.