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Tinnitus affects approximately 15-20% of the global population, with many seeking nutritional interventions for symptom relief. This article examines the most studied supplements, their mechanisms of action, and clinical evidence.
Supplement | Proposed Mechanism | Typical Dosage | Study Count* |
---|---|---|---|
Zinc | Cochlear nerve function | 30-50 mg/day | 18 |
Ginkgo biloba | Improved circulation | 120-240 mg/day | 23 |
Magnesium | Nerve signal regulation | 300-500 mg/day | 12 |
Vitamin B12 | Myelin sheath support | 1000-5000 mcg/day | 9 |
Melatonin | Sleep quality improvement | 3-10 mg/day | 7 |
*Number of published clinical studies (1990-2023) |
Supplement | % Patients Reporting Improvement | Average Symptom Reduction | Evidence Level** |
---|---|---|---|
Zinc | 46% | 22% | B |
Ginkgo biloba | 37% | 18% | B |
Magnesium | 29% | 15% | C |
Vitamin B12 | 41% (in deficient patients) | 27% | B |
Combination therapies | 52% | 31% | A- |
**A=strong evidence, B=moderate, C=preliminary |
Supplement | Common Side Effects | Drug Interactions | Recommended Duration |
---|---|---|---|
Zinc | Nausea, copper depletion | Antibiotics, diuretics | 3-6 months |
Ginkgo biloba | Headache, dizziness | Blood thinners | 4-12 weeks |
Magnesium | Diarrhea, cramping | Cardiac medications | Continuous |
High-dose B12 | Acne, energy spikes | None significant | As needed |
Melatonin | Drowsiness, dreams | Sedatives | 1-3 months |
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